Test for Pharmacology Experiment 2020 - 在线考试测评模板

Q1:1. The correct way for the rabbit to catch is: one hand to grasp ( ), the other hand to hold its hips, so that the rabbit will be keep seated（10分）

A. rabbit ear

B. neck back skin

C. rabbit head

D. rabbit upper limb

Q2:2. In the animal test, it is usually required to number the animals with ( )（10分）

A. 5% picric acid

B. 20% picric acid

C. 20 % Urethan

D. 5 % Urethan

Q3:3. Dye at the middle of the mouse back which means number ( )（10分）

A. 2

B. 4

C. 6

D. 8

Q4:4. Whichs correct about concentration of drug ( )（10分）

A. 5％ glucose -100ml solution contain 5g glucose

B. 5％ glucose -100L solution contain 5g glucose

C. 5％ glucose -100dL solution contain 5g glucose

D. 5％ glucose -1L solution contain 5g glucose

Q5:5. About the experiment “Determination of ED50 and LD50 of Pentobarbital Sodium”, Which of the following statements is true ( )（10分）

A. Righting reflex disappear means this mouse already slept.

B. Righting reflex appear means this mouse already slept

C. Take 60 mice, divided into 6 groups, each group received the same dosage.

D. The therapeutic index (TI) is equal to ED50 / LD50.

Q6:6. How long does the blood collection time of the pharmacokinetic model need to be maintained? ( )（10分）

A. 1 half-life of the drug

B. 2half-life of the drug

C. More than 5 half-lives of the drug

D. More than 3 half-lives of the drug

Q7:7. What is the main metabolic enzymes of Metoprolol? ( )（10分）

A.CYP1A2

B.CYP 3A4

C.CYP2D6

D.CYP2A6

Q8:8. About the experiment: Metoprolol for the treatment of hypertension and its pharmacokinetic parameters detection. Which of the following statements is true ( )（10分）

A. There are 4 patients in this experiment.

B. There are 3 patients in this experiment.

C. There are 2 patients in this experiment.

D. There are 1 patients in this experiment.

Q9:9. About the pharmacokinetic parameters of metoprolol in patients, which of the following statements is true.( )（10分）

A. The AUC of poor metabolizers is smaller than ones of wild metabolizers.

B. The AUC of poor metabolizers is bigger than ones of wild metabolizers.

Q10:10. Whichs correct about concentration of drug ( )（10分）

A. 75％ alcohol means 100ml solution contains 25ml dehydrated alcohol

B. 25％ alcohol means 100ml solution contains 75ml dehydrated alcohol.

C. 90％ alcohol means 100ml solution contains 10ml dehydrated alcohol

D. 75％ alcohol means 100ml solution contains 75ml dehydrated alcohol

Q11:ID and Name

A1